Sulfadimethine
Structural formula
| Business number | 018Y |
|---|---|
| Molecular formula | C12H14N4O2S |
| Molecular weight | 278.33 |
| label |
Sulfadimidine solution, Sulfamethazine solution, antibacterial growth promoter |
Numbering system
CAS number:57-68-1
MDL number:MFCD00006066
EINECS number:200-346-4
RTECS number:None
BRN number:None
PubChem number:24844985
Physical property data
1. Properties: white or yellowish crystal or powder. Odorless, slightly bitter in taste, and gradually darkens in color when exposed to light.
2. Density (g/mL, 25/4℃): Undetermined
3. Relative vapor density (g/mL, air=1): Undetermined
4. Melting point (ºC): 176
5. Boiling point (ºC, normal pressure): Undetermined
6. Boiling point (ºC, 5.2kPa): Undetermined
7. Refractive index: Undetermined
8. Flash point (ºC): Undetermined
9. Specific rotation (º): Undetermined
10. Autoignition point or ignition temperature (ºC): Undetermined
11. Vapor pressure (kPa, 25ºC): Undetermined
12. Saturated vapor Pressure (kPa, 60ºC): Undetermined
13. Heat of combustion (KJ/mol): Undetermined
14. Critical temperature (ºC): Undetermined
15. Critical pressure (KPa): Undetermined
16. Log value of oil-water (octanol/water) partition coefficient: Undetermined
17. Explosion upper limit (%, V/V): Undetermined
18. Lower explosion limit (%, V/V): Undetermined
19. Solubility: Almost insoluble in water (Solubility: 29℃, 150mg/100ml; 37℃, 192mg/100ml), this product is soluble in hot ethanol, insoluble in ether, and soluble in dilute acid or dilute alkali solution.
Toxicological data
None
Ecological data
None
Molecular structure data
1. Molar refractive index: 72.39
2. Molar volume (cm3/mol): 199.8
3. Isotonic specific volume (90.2K): 580.9
4. Surface tension (dyne/cm): 71.4
5. Polarizability (10-24cm3): 28.69
Compute chemical data
1. Reference value for hydrophobic parameter calculation (XlogP): None
2. Number of hydrogen bond donors: 2
3. Number of hydrogen bond acceptors: 6
4. Number of rotatable chemical bonds: 3
5. Number of tautomers: 5
6. Topological molecule polar surface area 106
7. Number of heavy atoms: 19
8. Surface charge: 0
9. Complexity: 377
10. Number of isotope atoms: 0
11. Determine the number of atomic stereocenters: 0
12. Uncertain number of atomic stereocenters: 0
13. Determined number of chemical bond stereocenters: 0
14. Uncertain chemical bond stereocenters Quantity: 0
15. Quantity of covalent bond units: 1
Properties and stability
None
Storage method
This product should be sealed and stored in a cool, dry place away from light.
Synthesis method
1. Obtained from the cyclization of sulfamidine and acetylacetone.
2.Using sulfamidine as raw material, it is obtained by cyclization with acetylacetone.
Purpose
1. Used to prevent and treat infections such as Staphylococcus aureus and lytic Streptococcus. It has an inhibitory effect on bacteria such as hemolytic Streptococcus and Pleurococcus. It is mainly used to treat avian cholera, avian typhoid, chicken coccidiosis, etc.
2.Used as an antibacterial agent to prevent and treat infections caused by staphylococci and hemolytic streptococci, and suitable for the treatment of hemolytic streptococci, meningococci, and pneumonia Cocci and other infections. Mainly used to treat avian cholera, avian typhoid, chicken coccidiosis, etc.
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